Hi Larry

I don't have time for all the details now, but most of the information is in the manuals. 
I will try to provide a skeleton overview to get you started, and others can help fill in the details as you try to do this.

General guidelines, based on Windows environment, with default Sesame settings:

1.  One system on your network should be designated as the Sesame Server station.  This machine would generally be running constantly so that it can "serve" the Sesame data to the other client machines.

2.  The Sesame Server should have lines in the Startup Folder that starts the Sesame Server when it starts up.
Something like this: C:\Sesame\Program\sesame.exe  -server ServerName:20000:20001.  This can be done with a single line batch file or a shortcut to a desktop icon would be better.

3.  Once the Sesame Server is started, it should not need to be stopped unless doing a Reconciliation to a database or if there is a need to shut down that machine.  Stopping and starting can be covered later.  (See Tips in November 2006 issue of Inside Sesame).

4.  On each of the clients, each Sesame user should have lines in their Startup folder that starts the Sesame Clients.  Something like this: C:\Sesame\Program\sesame.exe -client ServerName:20000:20001.  This can be done with a single line batch file or a shortcut to a desktop icon would be better.

5.  The startup command lines in the Startup folders can also define a specific database to be opened.  It may be easiest to make shortcuts for the Server and the Client on the desktop, and then make a link to those shortcuts in the Startup folders.

6.  The s_conf file should be copied into the C:\Sesame\ folder on the Sesame Server workstation only.  The documentation may refer to s_conf.cnf file.  This is the same file.  Explanation for difference is not needed now.  It is a function of a Windows setting.
EDIT ED NOTE:  The s_conf file should be copied into the Current Working Directory (CWD) that is noted in the "Start In" field in the shortcut for the Sesame Server icon.  Default is probably C:\Sesame.  The original info indicated C:\Sesame\Program\ folder as that was the CWD on the installation I was looking at when I replied.  Sorry for any confusion.

7.  Make sure that all users on workstations use the Client icon to start Sesame and do not use the normal sesame.exe command by itself.  Again, make shortcuts on the desktop and the Start Menus. 

8.  Users should be trained to exit Sesame normally when they leave their stations.  This will disconnect them from the Sesame Server and that will make it safer to shut down the Sesame Server if necessary.

Gotta run, hope this was helpful

Hi Ray .... Thanks for correcting info re s_conf location.

To clear it up further,
Accepted: The s_conf file would go into C:\Sesame\ folder as a result of default installations.

But if shortcut to Server uses Current Working Directory (CWD) = C:\Sesame\Program\ folder,  should it go into the CWD folder instead? 

I have an installation where s_conf is in C:\Sesame\Program\ folder, but that is the CWD for the Server, not C:\Sesame.
And it appears to be workking correctly for many months.

Thanks for confirming that.

I will modify my initial reply to include that information. 
I knew I had it in \Program\ folder, but forgot that it was not the default CWD.

I would also suggest the the nstallation instructions for the s_conf.cnf file (sesame network inst guide.pdf) should be modified to explain that.  The instructions would be more correct to say copy the file to the CWD that is noted in the Server shortcut.

Thanks again....

Hello Larry,

There should now be two sesame icons on the server computer. One for the Sesame Server and one for the Sesame Client.  Make sure that the one for the Sesame Client is running as client to the Sesame Server.

The basics of your icons should be as follows, with MotherShip being the name of the computer...

Sesame Server icon on the Server computer
Target: C:\Sesame\Program\sesame.exe -server MotherShip
Start in: C:\Sesame

Sesame Client icon on the Server computer
Target: C:\Sesame\Program\sesame.exe -client MotherShip
Start in: C:\Sesame

Sesame Client icon on the Client computer
Target: C:\Sesame\Program\sesame.exe -client MotherShip
Start in: C:\Sesame

-Ray